Fig. 2.

Taxa-specific modifications of TERT domains. TERT canonical motifs from representative metazoan phyla, early-branching metazoans and unicellular relatives of metazoans were annotated in colour codes: TEN domain GQ motif (purple); TRBD domain CP (dark green), QFP (blue) and T (light green) motifs; reverse transcriptase domain motifs 1 (brown), 2 (yellow), A (dark blue), B′ (sky blue), C (black), D (orange) and E (pink). a Deuterostome TERT canonical motifs. b Protostome, early-branching metazoans and unicellular eukaryotes canonical motifs. Motif annotations were drawn according to scale based on multiple sequence alignments performed using MAFFT