Table 1.
Linage disequilibrium (LD) of the combined studied SNPs in PD patients and healthy controls
| Control group | PD group | ||||||
|---|---|---|---|---|---|---|---|
| rs4633 | rs4818 | rs4680 | rs4633 | rs4818 | rs4680 | ||
| rs6269 | D’ | 0.90 | 0.94 | 0.77 | 0.91 | 0.98 | 1.00 |
| LOD | 8.05 | 48.14 | 4.84 | 4.43 | 48.84 | 5.49 | |
| r 2 | 0.18 | 0.85 | 0.12 | 0.14 | 0.92 | 0.16 | |
| rs4633 | D’ | - | 1.00 | 0.95 | - | 0.91 | 1.00 |
| LOD | - | 10.20 | 41.80 | - | 3.85 | 49.53 | |
| r 2 | - | 0.21 | 0.83 | - | 0.13 | 0.96 | |
| rs4818 | D’ | - | - | 0.94 | - | - | 1.00 |
| LOD | - | - | 7.47 | - | - | 4.88 | |
| r 2 | - | - | 0.17 | - | - | 0.16 | |
The LD pattern of the studied COMT SNPs was analyzed in Haploview. D' and r2: measures of linkage disequilibrium between two genetic markers. LOD the logarithm of the odds for LD