Table 4.
Significant correlations between changes in biochemical parameters and changes in methylation levels following an n-3 FA supplementation
| CpG site ID (gene, positiona) | ∆Triglyceride | ∆TC/HDL-C | ∆Glucose |
|---|---|---|---|
| ∆cg00011856 (IGFBP5, Chr2:217560946) | 0.39 (0.023)b | 0.36 (0.042) | – |
| ∆cg05655647 (ATF1, Chr12:51157023) | -0.35 (0.047) | – | – |
| ∆cg24455383 (AKT3, Chr1:243736307) | – | 0.42 (0.016)b | – |
| ∆cg15656521 (HDAC4, Chr2:239970617) | – | – | 0.35 (0.043) |
Results are R (P value)
Abbreviations: HDL-C high-density lipoprotein cholesterol, TC total cholesterol
aAll positions are from the Genome Build 37
bCorrelation remains significant after adjustments for age, sex, and body mass index