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In silico protein structure and function alterations due to altered genotypes confirmed by sanger sequencing. a- d Ab-initio models for wild type (WT) and mutant (MUT) proteins for AcrR, KdpD and PabC using ROBETTA and homology model for RpsL. e 3DLigandSite representation of the ligand binding residues (blue) including Ser238 among others, lost in the mutated variant of pabC gene as shown in (d)
