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. 2017 Apr;15(3):409–416. doi: 10.2174/1570159X14666160607101400

Table 2. Clinical characteristics of the sample.

Characteristics BD
(n= 86)
BD with PSU
(n= 63)
BD with AUD
(n=69)
F or χ2 df p
BDI: n (%) 42
(48.83)
23
(36.50)
19
(27.53)
7.48 2 0.02
Age at onset of illness: mean ± (SD) 26.33
(9.81)
27.92
(10.08)
31.54
(8.24)
4.26 2 0.01
Depressive onset of illness: n (%) 43
(50.00)
39
(61.90)
48
(69.56)
6.27 2 0.04
Duration of illness (years): mean± (SD) 19.56
(12.31)
15.57
(11.10)
16.31
(10.90)
2.28 2 0.10
Number of episodes: mean± (SD) 5.15
(3.62)
6.60
(5.79)
5.54
(5.12)
1.51 2 0.22
Number of hospitalisations: mean± (SD) 1.89
(2.38)
3.41
(5.75)
1.08
(2.47)
6.39 2 0.002
HAM-D score: mean ± (SD) 5.83
(3.25)
6.11
(3.34)
10.86
(6.81)
18.95 2 <0.0001
YMRS score: mean ± (SD) 3.06
(2.11)
3.14
(1.87)
3.62
(2.28)
0.64 2 0.52
Drugs:
    Antidepressants: n (%) 31
(36.04)
23
(36.50)
13
(18.84)
6.71 2 0.03
    Mood stabilizers/anticonvulsants: n (%) 76
(88.37)
58
(92.06)
66
(95.65)
2.69 2 0.26
    Antipsychotics: n (%) 51
(59.30)
26
(44.82)
13
(18.41)
25.90 2 <0.0001
    Benzodiazepines: n (%) 11
(12.79)
11
(17.46)
3
(4.34)
5.82 2 0.06

Legend: BD = Patients with bipolar disorders; PSU= polysubstance use; AUD= alcohol use disorder; S.D.=Standard deviation; df=Degrees of freedom.