Figure 4. PEG-PLGA nanoparticles present a diameter of 50 nm, with blunt edges, and can be localized inside the cell.
TEM images from ARPE-19 cells treated with PEG-PLGA NPs. (A) Characterization of size and shape of PEG-PLGA NPs. The hydrodynamic diameter was 50 nm, as measured by light scattering. Edges were blunt, without sharp spicules. (B) ARPE-19 cells treated with PEG-PLGA evidenced presence of the NPs within the cellular compartment, most likely in the endosomal system (arrows).
