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. Author manuscript; available in PMC: 2017 Apr 26.
Published in final edited form as: Semin Ophthalmol. 2016;31(1-2):1–9. doi: 10.3109/08820538.2015.1114865

Figure 5. PEG-PLGA nanoparticles are internalized and can be localized in the lysosomes, mitochondria, and endoplasmic reticulum.

Figure 5

Confocal microscopy images of ARPE-19 cells treated with Rhodamine 6G-loaded PEG-PLGA NPs and stained with different organelle stains. (A-C) Rhodamine 6G-loaded PEG-PLGA NPs can be observed at all z-planes inside the cells. These NPs can also be co-localized in the lysosomes (D-F), mitochondria (G-I), and endoplasmic reticulum (J- L), as seen in the merged signal with their respective trackers.