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. 2017 Mar 2;37(5):949–956. doi: 10.1161/ATVBAHA.116.308763

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© 2017 The Authors.

Arteriosclerosis, Thrombosis, and Vascular Biology is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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Figure 4. — Reticulated platelets display elevated reactivity in response to both arachidonic acid (AA) and ADP. The proportion of reticulated platelets among nonaggregated platelets was assessed by flow cytometry in platelet-rich plasma incubated with vehicle, (A) AA, or (B) ADP. C, Representative flow cytometric images of nonreticulated and reticulated (mRNA stain green) single platelets (red), as well as aggregates formed in response to ADP. Scale bars, 7 μm. Data presented as individual data points with overlaid mean±SEM and compared by paired t test (n=6; *P<0.05, ***P<0.001).