Table 3.

Inclusion and exclusion criteria of empirical (CE) papers.

Inclusion	Exclusion
Years 2000–2016	Reviews
Journal articles	Non-English language studies
Cost-effectiveness/utility studies	Conference abstracts
Studies in advanced, mortally ill patients (EOL period during which a person’s condition is actively deteriorating and when death is expected)	Study protocols
Studies written from palliative care paradigm	BSC studies
	Studies in non-human or children
	Broader palliative care studies
	Broader health economic studies (without CE analyses)
	Chronic/allergic/non-EOL diseases
	First-line/primary treatments
	Critical/intensive care studies
	Studies about predictive testing/prevention/screening
	Studies on developing/evaluating new interventions

CE: cost-effectiveness; EOL: end of life; BSC: best supportive care.