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. Author manuscript; available in PMC: 2017 Apr 26.
Published in final edited form as: Science. 2017 Mar 31;355(6332):1433–1436. doi: 10.1126/science.aah4115

Fig. 1. Divergence in gene expression levels and cell-to-cell variability among naive CD4+ T cells isolated from two species of mice.

Fig. 1

(A) Single cells were isolated from spleens of young (~3 month) and old (~21 month) individuals of two mouse sub-species, and sequenced before or after activation (13) ; (B) Species-specific tSNE clustering of naive CD4+ T cells from young animals; (C) Representative heatmap of 30 genes and 30 cells randomly selected from young animals from both species shows species-specific variation; (D) Violin plots show distribution of expression levels of selected, species-specifically transcribed genes (grey background).