Table I.
Cell type | Surface marker | WT (%) | Stx11-/- (%) | |
---|---|---|---|---|
Spleen | CD4+ T cells | CD3+ CD4+ | 17.78 ± 0.49 | 19.22 ± 1.13 |
CD8+ T cells | CD3+ CD8+ | 12.40 ± 0.97 | 12.94 ± 0.68 | |
B cells | B220+ | 49.30 ± 4.16 | 51.16 ± 3.24 | |
Immature B cells | B220+IgMhighIgDlow | 12.07 ± 2.44 | 15.12 ± 4.72 | |
Mature B cells | B220+IgMlowIgDhigh | 33.46 ± 4.59 | 40.39 ± 1.90 | |
Granulocytes | CD11b+ Gr-1high | 2.92 ± 0.23 | 2.95 ± 0.24 | |
NK cells | CD3- DX5+ | 2.21 ± 0.36 | 1.99 ± 0.31 | |
DC | CD11c+ | 3.77 ± 0.19 | 3.55 ± 0.25 | |
Macrophages | Gr-1-CD11b+ | 4.17 ± 0.21 | 4.38 ± 0.39 | |
Lymph node | CD4+ T cells | CD3+ CD4+ | 24.69 ± 3.23 | 25.91 ± 1.26 |
CD8+ T cells | CD3+ CD8+ | 15.22 ± 1.58 | 15.51 ± 1.75 | |
B cells | B220+ | 50.90 ± 3.51 | 52.14 ± 2.15 | |
NK cells | CD3- DX5+ | 0.91 ± 0.12 | 0.93 ± 0.13 |
Splenocytes and lymph node cells from WT and Stx11-/- mice were analyzed by flow cytometry.
Values represent the mean ± SEM percentage of cell subsets in the spleen (n=8) and lymph nodes (WT n=7; Stx11-/- n=6) and are the summary of 3 experiments performed.