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. Author manuscript; available in PMC: 2017 Apr 26.
Published in final edited form as: Small. 2016 Feb 22;12(15):1968–1992. doi: 10.1002/smll.201503396

Table 2.

Examples of dye loaded NPs prepared from preformed polymers

Polymer Solvent Homogenization Dye (wt%) Size (nm) Ref.
Emulsification solvent evaporation
PLGA, PLGA-PEGa CH2Cl2 sonication AIE1 (10%) 180-210 [49]
Eudragit Eb CH2Cl2 sonication NDA, Nile red (2.5%) 190-210 [50b]

Nanoprecipitation
PLGA acetonitrile stirring Rhodamine B (5%) 40 [22c, 23]
PLGA-PEG DMSO - DiD, DiR (2%) 50-80 [57]
P(MMA-co-MAS) (98.5:1.5) acetonitrile stirring Rhodamine B (5%) 15 [54b]
DSPE-PEG THF sonication Different AIE (30%) 30-80 [59a, 69]
C18PMH THF sonication Squaraine (0.5%) 16 [70]

Self-assembly
PMAA-b-PS, PEG-b-PCL, PEG-b-PS THF stirring AIE5 (20%) 63-85 [62b]
PEG-b-PVBA DMF Stirring Fluorescein, Cy7, HL800 25 [62a]
HPMA, MATMA, TFMA copolymer DMSO Stirring AIE dye (4-40%) 7-25 [64a]
a

PVA (0.25, 2.5 %w/v)

b

PVA (0.3-3 %w/v); NDA: naphthalene-2,3-dicarboxaldehyde; MAS: methacrylate ethylsulfonate; HPMA: N-(2-hydroxypropyl) methacrylamide; MATMA: [2-(methacryloyloxy)ethyl]trimethylammonium chloride; TFMA: 2,2,2-trifluoroethyl methacrylate; PVBA: poly(4-vinyl benzaldehyde).