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. 2017 Apr 26;12(4):e0174426. doi: 10.1371/journal.pone.0174426

Table 2. Treatment episodes for two example patients under three different scenarios.

Scenario Patient ID Episode number Date of episode start Number of gap days after or at the end of the episode Number of days in the episode (duration) Date of episode end
A 37 1 2036-04-10 122 608 2037-12-09
76 1 2035-12-13 144 434 2037-02-19
2 2037-07-13 32 152 2037-12-12
B 37 1 2036-04-10 61 50 2036-05-30
2 2036-07-30 67 216 2037-03-03
3 2037-05-09 66 30 2037-06-08
4 2037-08-13 122 118 2037-12-09
76 1 2035-12-13 144 434 2037-02-19
2 2037-07-13 32 152 2037-12-12
C 37 1 2036-04-10 56 211 2036-11-07
2 2037-01-02 122 463 2038-04-10
76 1 2035-12-13 0 374 2036-12-21
2 2036-12-21 60 234 2037-08-12
3 2037-10-11 32 62 2037-12-12

A: 90-day gap, no change of treatment episode when medication changes;

B: 60-day gap, no change of treatment episode when medication changes;

C: 180-day gap, new treatment episode when medication changes

All three scenarios refer to a 2-year follow-up window from the first medication event, with carry-over within the observation window, only for the same medication, considering dosage change.