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The effect of different treatments on the immune response of animals. The measured serum levels (pg/ml) of interferon-γ (IFN-γ), interleukin-2 (IL-2), IL-4 and IL-10 from animals treated once a day with 80 mg/kg metformin (MET), 50 mg/kg curcumin (CUR), combination of both and a vehicle (control). Each treatment was performed in duplicate. Results are expressed as means (bars) ± SEM (lines). The asterisks represent significant values.
