Table 1. Vaccine biological effects.

Outcome	Measured effect at the individual level
SE (susceptibility effect: efficacy of reducing worm accumulation)	% reduction in worm accumulation
FE (fecundity effect: efficacy of reducing eggs released to environment)	% reduction in worm fecundity
ME (mortality effect: efficacy of increasing worms’ in vivo mortality)	% increase in worm mortality
D (durability)	The mean duration in years of the vaccine effect represented by the efficacies.

Individual level efficacies of potential schistosomiasis vaccines, as could be measured in Phase 3 vaccine randomized controlled trials.