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. 2017 Apr 26;12(4):e0176079. doi: 10.1371/journal.pone.0176079

Fig 1. Conceptual approach of the cell micropatterning method used in this study.

Fig 1

Subnanoliter volumes of an ECM proteins mixture are deposited on a flat substrate with pre-defined custom spatial patterns. The amount of the deposited mixture as well as its spatial location can be controlled precisely via customizable dispensing parameters for flexibility in controlling the population size and proximity to other adjacent populations.