Changes in mRNA expression of (A) IL-1α and (B) IL-6 (C) MCP-1 in MEHP (667 mg/kg p.o, black bars) or control (2 ml/kg corn oil, grey bars) treated rat seminiferous tubules at 3, 6, 12, and 24 h (n=6 per treatment per time point). IL-1α expression was significantly increased at 3 h. IL-6 expression was found to be significantly increased at 6 h. MCP- mRNA expression was significantly increased at 12 h. Statistical analysis was performed using two-way ANOVA for unmatched data with Sidak’s multiple comparison test and each MEHP-treated sample was compared to its time point control.