Table 4.
Gene expression cluster and clinical response
| Remission |
Response |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cluster | 6 mo | OR* (95% CI) |
P value |
12 mo | OR (95% CI) |
P value |
6 mo | OR (95% CI) |
P value |
12 mo | OR (95% CI) |
P value |
| All patients | 20/44 (45.5) |
21/38 (55.3) |
27/44 (61.4) |
25/38 (65.8) |
||||||||
| 1, 2 or 3 | 17/31 (54.8) |
4.048 (.929–17.63) |
.096 | 18/27 (66.7) |
5.333 (1.132–25.12) |
.037 | 23/31 (74.2) |
6.469 (1.553–26.94) |
.016 | 21/27 (77.8) |
6.125 (1.330–28.22) |
.024 |
| 4 or 5 | 3/13 (23.1) |
3/11 (27.3) |
4/13 (30.8) |
4/11 (36.4) |
||||||||
Frequencies are reported as n meeting endpoint / n in group (%)
*
Odds of attaining endpoint for patients in cluster 1, 2, or 3 compared to those in cluster 4 or 5.
CI, confidence interval; Cq, quantification cycle; OR, odds ratio