TARGETS | |
---|---|
GPCRs a | Enzymes c |
AT2 receptors | Adenylate cyclase |
B2 receptors | Akt (PKB) |
ETB receptors | COX |
RXFP1 receptors | eNOS |
Voltage‐gated ion channels b | iNOS |
IKCa (KCa3.1) | PI3K |
SKCa |
LIGANDS | |
---|---|
ACh | MMP2 |
Ang II | NO |
BK, bradykinin | PGI2 |
cGMP | PlGF, placental growth factor |
cAMP | Relaxin |
ET‐1 | TNF‐α |
Indomethacin | VEGF |
L‐NAME |
These Tables list key protein targets and ligands in this article that are hyperlinked to corresponding entries in http://www.guidetopharmacology.org, the common portal for data from the IUPHAR/BPS Guide to PHARMACOLOGY (Southan et al., 2016), and are permanently archived in the Concise Guide to PHARMACOLOGY 2015/16 (a,b,cAlexander et al., 2015a,b,c).