Model of ML290 binding with human RXFP1 receptors. The agonist ML290 is shown in stick form (C atoms in cyan, O and N atoms are shown in red and blue). Shown are key residues within the RXFP1 receptor involved in binding interactions. TM3 (brown), TM5 (blue), TM6 (orange), TM7 (red), ECL2 (green) and ECL3 (magenta) are shown in different colors.