Table 1.
Baseline demographics in patients with OCD by treatment type
| Demographics | General group* | Phenotypic group† | OR (95% CI) or MD (95% CI)‡ | p value§ | |||||
|---|---|---|---|---|---|---|---|---|---|
| Conservative | Unilateral | Bilateral | Multiple | Total | Less potent | Potent | |||
| Number of patients (%) | 20 (19) | 50 (49) | 21 (20) | 12 (12) | 103 (100) | 70 (70) | 33 (32) | ||
| Gender | 1.1 (0.4–2.8) | 0.873 | |||||||
| Male (%) | 15/20 (75) | 37/50 (74) | 19/21 (90) | 6/12 (50) | 77/103 (75) | 52/70 (74) | 25/33 (76) | ||
| Female (%) | 5/20 (25) | 13/50 (26) | 2/21 (10) | 6/12 (50) | 26/103 (25) | 18/70 (26) | 8/33 (24) | ||
| Laterality | 0.9 (0.3–3.0) | 0.855 | |||||||
| Right | 11/20 (55) | 26/50 (52) | N/A | 6/12 (50) | 43/103 (42) | 37/70 (53) | 6/12 (50) | ||
| Left | 9/20 (45) | 24/50 (48) | N/A | 6/12 (50) | 39/103 (38) | 33/70 (47) | 6/12 (50) | ||
| Age, average (years; ± SD) | 12 (± 2) | 14 (± 2) | 12 (± 2) | 14 (± 2) | 13 (± 2) | 14 (± 2) | 13 (± 2) | −1 (−2.0 to −0.2) | 0.020 |
| Lesion location | 2 (0.8–4.9)** | 0.131 | |||||||
| Medial femoral condyle (%) | 14/20 (70) | 26/50 (52) | 17/21 (81) | 7/12 (58) | 64/103 (62) | 40/70(57) | 24/33 (72) | ||
| Lateral femoral condyle (%) | 5/20 (25) | 11/50 (22) | 4/21 (19) | 2/12 (17) | 22/103 (21) | 16/70 (22) | 6/33 (18) | ||
| Trochlea (%) | 0/20 (0) | 9/50 (18) | 0/21 (0) | 2/12 (17) | 11/103 (11) | 9/70 (13) | 2/33 (6) | ||
| Patella (%) | 1/20 (5) | 3/50 (6) | 0/21 (0) | 1/12 (8) | 5/103 (5) | 4/70 (6) | 1/33 (3) | ||
| Unspecified (%) | 0 | 1/50 (2) | 0/21 (0) | 0/12 (0) | 1/103 (1) | 1/70 (1) | 0/33 (0) | ||
| Secondary procedures, number (%)∥ | N/A | 18 (36) | 3/13 (23)** | 8/12 (67) | 29/75 (39) | 18/50 (36) | 11/25 (44)** | 1.4 (0.5–3.7) | 0.504 |
| Number of immediate family members, average number per patient (± SD)¶ | 4 (± 1) | 4 (± 1) | 4 (± 1) | 4 (± 1) | 4 (± 1) | 4 (± 1) | 4 (± 1) | −0.1 (−0.5 to 0.4) | 0.777 |
Data presented as numerator/denominator (frequency) or mean (± SD); * per methods section, groups correspond to nonoperative management, unilateral lesions advanced to surgery, bilateral lesions managed either conservatively or surgically, and patients who underwent multiple procedures for the same lesion; †phenotypically less potent = conservative and unilateral groups; phenotypically severe = bilateral and multiple groups; ‡OR and MD calculated for phenotypically severe group as compared to less severe group; §p values correspond to intergroup differences calculated by Fisher’s exact/chi square text or students t-test, as indicated; ∥at the time of the first procedure; includes loose body removal, lateral meniscus repair, etc; of note, eight patients with bilateral lesions were managed conservatively without operative treatment; ¶immediate family includes parents and/or siblings; does not account for those with/without a history of OCD; **calculated for medial femoral condyle lesion as compared to all other locations; OCD = osteochondritis dissecans; OR = odds ratio; CI = confidence interval; MD = mean difference; N/A = not applicable.