Table 5.
Allergen source/allergens | Name/function | Sensitization frequency (%) | No. of patients | Reference |
---|---|---|---|---|
Apis mellifera | ||||
rApi m 1 | Phospholipase A2 | 79 57 78 78 72 97 |
34 175 100 23 144 100 |
Hofmann 2011 [37] Korosec 2011 [45] Sturm 2011 [47] Muller 2012 [44] Kohler 2014 [46] Muller 2009 [26] |
rApi m 2 | Hyaluronidase | 46 52 48 |
82 40 144 |
Hofmann 2011 [37] Sturm 2011 [47] Kohler 2014 [46] |
rApi m 3 | Acid phosphatase | 38 50 |
40 144 |
Grunwald 2006 [55] Kohler 2014 [46] |
nApi m 4 | Melittin | 27 42 23 |
82 40 144 |
Hofmann 2011 [37] Sturm 2011 [47] Kohler 2014 [46] |
rApi m 5 | Dipeptidylpeptidase IV | 60 58 |
35 144 |
Blank 2010 [56] Kohler 2014 [46] |
rApi m 6 | Serine protease inhibitor | 26 | 31 | McIntyre 2012 [57] |
rApi m 10 | Icarapin | 49 62 |
68 144 |
Blank 2011 [58] Kohler 2014 [46] |
rApi m 11a (0101) rApi m 11b (0201) |
Major royal jelly protein 8/9 | 15/34 | 47 | Blank 2012 [59] |
rApi m 12 | Vitellogenin | 44 | 45 | Blank 2013 [60] |
Combination | rApi m 1, rApi m 2, rApi m 3, nApi m 4, rApi m 5, rApim 10 | 94 | 144 | Kohler 2014 [46] |
Combination | rApi m 1, rApi m 2, rApi m 3, rApi m 5 | 92 | 86 | Cifuentes 2014 [36] |
Vespula vulgaris | ||||
rVes v 1 | Phospholipase A1 | 79 54 39 58 |
14 148 86 109 |
Seismann 2010 [35] Ebo 2013 [39] Cifuentes 2014 [36] Hofmann 2011 [40] |
rVes v 2a (0101) rVes v 2b (0201) |
Hyaluronidase Hyaluronidase**inactive isoform |
5 28 20 |
41 86 41 |
Seismann 2010 [35] Cifuentes 2014 [36] Seismann 2010 [35] |
rVes v 3 | Dipeptidylpeptidase IV | 57 50 |
35 86 |
Blank 2010 [56] Cifuentes 2014 [36] |
rVes v 5 | Antigen 5 | 90 90 90 87 85 90 |
59 148 308 86 200 109 |
Hofmann 2011 [37] Ebo 2013 [39] Vos 2013 [28] Cifuentes 2014 [36] Korosec 2012 [38] Hofmann 2011 [40] |
rVes v 6 | Vitellogenin | 39 | 28 | Blank 2013 [59] |
Combination | rVes v 1 + r Ves v 5 | 93 92 98 96 96 |
14 200 148 308 109 |
Seismann 2010 [35] Korosec 2012 [38] Ebo 2013 [39] Vos 2013 [28] Hofmann 2011 [40] |
Combination | rVes v 1, rVes v 2, Ves v 3, rVes v 5 | 95 | 86 | Cifuentes 2014 [36] |