Figure 2.

MRS voxel placement, MRS spectrum with fit, and correlation plot of GABA and skin conductance responses. (A) The MRS voxel was planned on the anatomical scan of each participant. The 40 × 20 × 20 mm³ box was closely aligned with the corpus callosum in the dACC. (B) GABA was fitted onto the spectrum using AMARES in jMRUI. GABA was fitted using a Gaussian function at 3.0 ppm. (C) The correlation of dACC GABA concentrations and skin conductance responses to the CS+ relative to the CS− during fear recovery revealed a positive relation (r_s = 0.28; P = 0.04).