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. 2017 Apr 27;11:202. doi: 10.3389/fnhum.2017.00202

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Copyright © 2017 Levar, van Leeuwen, Puts, Denys and van Wingen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Functional connectivity during the recovery of fear. (A) Psychophysiological interactions with the right amygdala seed region during fear recovery revealed a negative voxel-wise correlation of GABA mediated amygdala-vmPFC connectivity during fear recovery (MNI_x,y,z = 2, 52, −2; P_SVC < 0.05). Threshold for displaying the images is set at P = 0.005, uncorrected. (B) Correlation plot of dACC GABA levels and deactivation of the vmPFC showing that high GABA levels are correlated with diminished amygdala-vmPFC connectivity compared to low GABA levels.