Figure 4.
SchLAH inhibits migratory potential of HCC cells through RhoA and Rac1. (a, b) Changes of gene expression were analyzed by a Cancer Motility RT 2 Profiler PCR array. The downegulated genes that fold change >1.5 in HepG2‐SchLAH and Hep3B‐SchLAH were intersected to generate an overlapping gene signature. (c–f) Overlapping genes in (b) were confirmed by qRT‐PCR in HepG2, Hep3B, Huh7, and SMMC7721 cells. β‐actin serves as a control. Values are mean ± standard deviation (n = 3). *P < 0.05, **P < 0.01.