Figure 6.

Histone deacetylation contributes to SchLAH downregulation. (a, b) HepG2 and Huh7 cells were stimulated with different concentrations of the histone deacetylase inhibitor trichostatin A (TSA) for 24 h. The expression of SchLAH was detected using qRT‐PCR and normalized to β‐actin. (c) ChIP analyses were conducted on the SchLAH promoter regions using anti‐acetyl‐histone H3 and anti‐acetyl‐histone H4. Enrichment was determined relative to input controls. Values are mean ± standard deviation (n = 3). *P < 0.05, **P < 0.01.