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. 2017 Apr 19;108(4):620–631. doi: 10.1111/cas.13177

Figure 4.

Figure 4

MiR‐155‐5p promotes hepatocellular carcinoma (HCC) malignancy through targeting PTEN. (a–e) Cell viability, the percentage of apoptotic cells, wound healing and transwell assays, and the expression of Bcl‐2, Bax, caspase‐9, MMP2 and MMP9 in Hep3B and HepG2‐transfected PTEN plasmid and PTEN siRNA with and without miR‐155‐5p mimics or inhibitor; the intensity of each band was quantified; the value under each lane indicates the relative expression level of the regulators; n = three repeats with similar results, *P < 0.05, **P < 0.01, ***P < 0.001 by Student's t‐test, versus inhibitor and mimics NC, respectively. #P < 0.05, ##P < 0.01, ###P < 0.001 by Student's t‐test, versus inhibitor + siRNA NC and mimics + PTEN vector control, respectively. PTEN, PTEN plasmid; siPTEN, PTEN siRNA.