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Effect of 4D5scFv-PE40 on SKBR-3 culture growth. Left-hand side: the relative viability of the monolayer culture after incubation with immunotoxin for 72 h. Right-hand side: the relative viability of the spheroid cells 168 h after the immunotoxin was added into the medium. Mean ±SEM, n = 6 for all experimental conditions.
