Table 2.
Statins | Defined Daily Doses | Mouse Model | |
---|---|---|---|
Effective Dose | Cancers (in literature) | ||
Simvastatin | 30 mg | 50 mg/kg/day * | melanoma [36] |
50 mg/kg/day * | colon cancer [37] | ||
Lovastatin | 45 mg | 10 mg/kg/day * | thyroid cancer [38] |
16 mg/kg/day * | ascites tumor [39] | ||
Fluvastatin | 60 mg | 40 mg/kg/day * | leukemia [40] |
15 mg/kg/day ** | breast cancer [41] | ||
Atorvastatin | 20 mg | 16 mg/kg/day ** | ascites tumor [42] |
10 mg/kg/day ** | prostate cancer [43] |
* oral, ** intraperitoneal.