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. 2017 Apr 13;2017:2184040. doi: 10.1155/2017/2184040

Figure 2.

Figure 2

(a) Histology of healing wound tissue by hematoxylin and eosin stain at the indicated time intervals in dorsal skin of inducible nitric oxide synthase (iNOS-) knockout (KO) mice and WT mice. (b) The thickness of the granulation tissue at the center zone was thinner in KO mice than in WT mice at days 6 and 8 with a statistically significant difference. (c) At the margin zone, the thickness of the granulation tissue was significantly thinner in KO mice than in WT mice at day 6. Open bars: WT, filled bars: KO (days 3, 11, and 14: n = 6; days 6, 8: n = 7 animals in each group). Mean ± standard deviation. ∗p < 0.05; ∗∗p < 0.01; bar, 1 mm.