. 2017 Apr 20;8(4):125. doi: 10.3390/genes8040125

Table 4.

T1D and a summary of association studies for SNPs within the genes CYP2R1, CYP27B1, DBP and cubilin.

Other Vitamin D System Components						Susceptibility to T1D SNPs
Author	Year	Population	Total	Case	Control		Comparison Groups
CYP2R1 gene
Ramos-Lopez et al. [88]	2007	German	203			rs10741657	T1D families
Ramos-Lopez et al. [88]	2007	German	578	284	294	rs10741657	T1D/control
Cooper et al. [57]	2011	British	1933			rs10741657, rs12794714	T1D families
Cooper et al. [57]	2011	British	18,955	8517	10,438	rs10741657, rs12794714	T1D/control
CYP27B1 gene
Ramos-Lopez et al. [90]	2004	German	572	252	320	rs10877012	T1D/control
Bailey et al. [91]	2007	Great Britain, Northern Ireland,	2774			rs10877012, rs4646536	T1D families
		Finland, USA, Norway, Romania
		Great Britain	16,612	7854	8758	rs10877012, rs4646536	T1D/control
Cooper et al. [57]	2011	British	1933			rs10877012	T1D families
Cooper et al. [57]	2011	British	18,955	8517	10,438	rs10877012	T1D/control
Hussei et al. [93]	2012	Egyptian	240	120	120	rs10877012	T1D/control
DBP (GC) gene
Ongagna et al. [96]	2001	Alsatian and North African origin	95	43	52	rs7041	T1D/control
Ongagna et al. [97]	2005	Alsatian and North African origin	178	110	68	rs7041	T1D/control
Cubilin gene
Ramos-Lopez et al. [99]	2010	German	400	200	200	rs3740165	T1D/control