Table 2.
Univariate Associations between NAFLD definition and selected covariates
| N | Meets NAFLD definition: Any (mild/moderate/severe) fatty infiltration or ALT > 25 IU/mL (males)or ALT >22 IU/mL (females) | P Value | ||
|---|---|---|---|---|
| No | Yes | |||
| Sex, n (%) | 0.57 | |||
| Male | 42 | 5 (11.9) | 37 (88.1) | |
| Female | 55 | 10 (18.2) | 45 (81.8) | |
| Age (category), n (%) | 1.00 | |||
| < 10 Years | 16 | 2 (12.5) | 14 (87.5) | |
| > =10 Years | 81 | 13 (16.0) | 68 (84.0) | |
| Total Cholesterol (mmol/L), mean (SD) normal | 97 | 4.3 (0.6) | 4.4 (0.8) | 0.63 |
| Triglycerides (mmol/L), mean (SD) | 96 | 1.1 (0.5) | 1.5 (0.9) | 0.01 |
| HDLC (mmol/L), median (IQR) | 97 | 1.0 (1.0–1.3) | 1.0 (0.9–1.2) | 0.98 |
| LDLC (mmol/L), mean (SD) normal | 96 | 2.7 (0.6) | 2.6 (0.8) | 0.72 |
| Non HDL Cholesterol (mmol/L), mean (SD) | 84 | 3.1 (0.6) | 3.3 (0.8) | 0.37 |
| HOMAIR, n (%) | 95 | 0.40 | ||
| < 3.16 | 9 (20) | 36 (80) | ||
| > = 3.16 | 6 (12) | 44 (88) | ||
| AST(IU/mL), median (IQR) | 95 | 23.5 (21.0–26.3) | 27.0 (21.0–31.5) | 0.18 |
| Adiponectin, median (IQR) | 96 | 16.1 (9.0–21.9) | 11.2 (7.3–18.3) | 0.23 |
| BMI Z Score, mean (SD) | 97 | 3.7 (1.3) | 3.8 (1.4) | 0.80 |
NAFLD Non-Alcoholic Fatty Liver Disease, ALT Alanine Aminotransferase, HDLC High Density Lipoprotein Cholesterol, LDLC Low Density Lipoprotein Cholesterol, HOMA IR Homeostatic Model Assessment Insulin Resistance, AST Aspartate aminotransferase, BMI Body Mass Index.