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. 2017 Apr 27;17:74. doi: 10.1186/s12890-017-0409-3

Table 4.

Mean healthcare cost per exacerbation in the 30 days after an exacerbation (US database only)

Total all-cause ($) Total asthma-related ($)
mean (SD) mean (SD)
Overall 1,368 (3,797) 520 (981)
GINA Step Step 1 1,265 (3,981) 446 (908)
Step 2 1,376 (3,978) 465 (874)
Step 3 1,253 (3,242) 433 (782)
Step 4 1,425 (3,817) 516 (828)
Step 5 1,814 (3,614) 902 (1,533)
Not classifiable/none 946 (1,628) 332 (377)
Exacerbations during the 12-month pre-index period <2 1,344 (3,836) 477 (861)
≥2 1,534 (3,516) 754 (1,451)
Severe uncontrolled asthmaa Yes 1,692 (3,233) 911 (1,563)
No 1,347 (3,831) 486 (905)
Severe uncontrolled eosinophilic asthmab Yes 2,040 (3,285) 1,073 (1,958)
No 1,692 (3,934) 615 (1,248)

aDefined as patients at GINA Step 4 or 5 with ≥2 exacerbations in the previous 12 months; bpatients with severe uncontrolled asthma criteria and blood eosinophil counts ≥300 cells/μl at baseline

GINA Global Initiative for Asthma, SD standard deviation