Table 2.
Baseline characteristics of study subjects
| Control (n = 37) [mean (range)] | Obese (n = 37) [mean (range)] | P | |
|---|---|---|---|
| Sex (female) [n (%)] | 31 (84) | 31 (84) | |
| Age, yr | 41.3 (23–63) | 41.6 (23–66) | 0.9 |
| BMI, kg/m2 | 22.1 (17.6–26) | 46.2 (35.6–68.6) | <0.0001 |
| AST, IU/l | 18.7 (12–32) | 17.9 (7–42) | 0.6 |
| ALT, IU/l | 15.8 (10–39) | 23.9 (7–58) | <0.001 |
| Total cholesterol, mg/dl | 178.4 (120–235) | 169.7 (112–239) | 0.18 |
| Triglycerides, mg/dl | 68.7 (34–145) | 150 (40–305) | <0.0001 |
| HDL-C, mg/dl | 69.5 (40–93) | 45.2 (27–79) | <0.0001 |
| LDL-C, mg/dl | 95.1 (34–151) | 95.1 (38–148) | 0.99 |
| Glucose, mg/dl | 77.5 (57–106) | 112.9 (75–259) | <0.0001 |
| Insulin, μU/ml | 2.42 (0.1–6.0) | 7.2 (0.4–17.9) | <0.0001 |
| HOMA-IR | 0.47 (0.02–1.4) | 1.92 (0.1–4.9) | <0.0001 |
| Hemoglobin A1c, % | 5.2 (4.6–5.8) | 6.4 (4.7–10.4) | 0.0001 |
| Adiponectin, ng/ml | 17,381 (5,041–37,197) | 7367 (3304–17304) | <0.0001 |
| CTRP7, ng/ml | 238 (4–1,237) | 515 (17–1079) | <0.0002 |
| Leptin, pg/ml | 11,870 (658–52,585) | 62,133 (12,879–163,543) | <0.0002 |
BMI, body mass index; AST, aspartate aminotransferase; ALT, alanine aminotransferase; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance. P values are calculated by two-tailed t-test.