Table 5.
Male |
Female |
|||||||
---|---|---|---|---|---|---|---|---|
LFD |
HFD |
LFD |
HFD |
|||||
WT (n = 6) | KO (n = 6) | WT (n = 11) | KO (n = 11) | WT (n = 12) | KO (n = 12) | WT (n = 11) | KO (n = 9) | |
Heart, g | 0.16 ± 0.02 | 0.20 ± 0.01 | 0.20 ± 0.01 | 0.22 ± 0.02 | 0.15 ± 0.01 | 0.15 ± 0.01 | 0.16 ± 0.02 | 0.14 ± 0.008 |
Kidney, g | 0.17 ± 0.01 | 0.18 ± 0.01 | 0.20 ± 0.006 | 0.21 ± 0.02 | 0.12 ± 0.003 | 0.12 ± 0.004 | 0.14 ± 0.005 | 0.14 ± 0.007 |
Liver, g | 1.58 ± 0.08 | 1.56 ± 0.1 | 3.10 ± 0.1 | 2.57 ± 0.2* | 1.07 ± 0.04 | 1.2 ± 0.08 | 1.30 ± 0.1 | 1.26 ± 0.1 |
Liver/BW | 0.04 ± 0.001 | 0.04 ± 0.002 | 0.06 ± 0.001 | 0.05 ± 0.002* | 0.01 ± 0.00 | 0.01 ± 0.002 | 0.03 ± 0.002 | 0.03 ± 0.001 |
eWAT, g | 0.83 ± 0.07 | 0.67 ± 0.07 | 0.77 ± 0.09 | 0.79 ± 0.09 | 0.31 ± 0.04 | 0.38 ± 0.06 | 1.88 ± 0.1 | 1.84 ± 0.1 |
iWAT, g | 0.65 ± 0.09 | 0.51 ± 0.09 | 1.58 ± 0.2 | 1.28 ± 0.1 | 0.23 ± 0.03 | 0.28 ± 0.04 | 1.36 ± 0.10 | 1.54 ± 0.1 |
Tibia, mm | 17.8 ± 0.15 | 17.9 ± 0.1 | 19.3 ± 0.2 | 19.5 ± 0.2 | 17.9 ± 0.08 | 17.8 ± 0.1 | 19.2 ± 0.20 | 18.9 ± 0.20 |
Values are means ± SE; n is number of mice. LFD, low-fat diet; HFD, high-fat diet; BW, body weight; eWAT, epididymal white adipose tissue; iWAT, inguinal white adipose tissue.
P < 0.05.