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. 2017 Apr 27;19:3. doi: 10.1186/s12575-017-0052-7

Table 1.

Functions of immune related lncRNAs

S. No. lncRNA Function Reference
1 Hotair Promotes cancer metastasis and progression via epigenetic variations in the chromatin state [31]
2 Lnc-IL7R Epigenetically regulates inflammation [15]
3 NRON Transcription regulator for immune regulation [33]
4 NeST/Tmevpg1 Epigenetically regulates the adaptive immunity through IFN-gamma [24, 34, 35]
5 IL1β Chromatin modulation. [14]
6 IL1β-RBT46 Regulates the homeostasis of IL-1β in monocytes [14]
7 IL1b-eRNA Expression of proinflammatory mediators e.g., CXCL8 and IL-1β [14]
8 PACER Involved in multiple processs related to regulation of immunogene expression [21]
9 LincRNA-COX2 Role in TLR-induced expression of interleukin-6 [7, 22]
10 Lnc-DC Required for the differentiation of monocytes to dendritic cells [20]
11 Lethe Upregulated during inflammation [19]
12 THRIL Regulate expression of tumour necrosis factor (TNF) in human monocytes [10, 23]
13 PAN epigenetically regulates viral gene expression and promotes the switch from latent to lytic infection [52, 54]
14 NRAV Modulation of transcription of multiple interferon-stimulated genes (ISGs) i.e,. MxA and IFITM3 [55]
15 NEAT1 Triggers transcriptional activation of IL-8 in response to viral infection [10]