Fig. 3.

Effects of Cx40 deletion on [Ca²⁺]_cyto in MCECs. A: typical record of the change in [Ca²⁺]_cyto in MCECs. 1st peak describes the rise in [Ca²⁺]_cyto by CPA treatment in the absence of extracellular Ca²⁺ (indirect indicator of [Ca²⁺]_ER), and 2nd peak indicates store-operated Ca²⁺ entry (SOCE). Data are described as a ratio (F₃₄₀/F₃₈₀). B–F: summarized data of resting level of [Ca²⁺]_cyto (B), Δ1st peak (C), AUC of 1st peak (D), Δ2nd peak (E), and AUC of 2nd peak (F) in MCECs of WT mice (n = 74 cells) and Cx40 KO mice (n = 96 cells). Data are means ± SE. *P < 0.05 vs. WT.