Fig. 6.

Acarbose attenuated the plasma insulin (top row) and blood glucose (bottom row) response (means ± SE) to licking for sucrose, maltose, and Polycose (experiment 4). Within each panel, we compared (at each time-point) the plasma insulin or blood glucose concentrations following oral stimulation with the carbohydrate (Carb) solution vs. its corresponding carbohydrate + 5 mM acarbose (Carb + acarbose) solution, using Sidak’s multiple comparisons test (#P < 0.05). We also compared the plasma insulin or blood glucose concentration at baseline (B) with that at each successive time-point, separately for each treatment group, using Dunnett’s multiple comparison test (*P < 0.05). For each experimental solution, we tested the following number of mice: sucrose (n = 6), sucrose + acarbose (n = 9), maltose (n = 8), maltose + acarbose (n = 9), Polycose (n = 8), and Polycose + acarbose (n = 9).