Table 2.

Characteristics of the fetal pancreas

	Control	Anemic
Pancreas weight, g	2.96 ± 0.25	3.08 ± 0.20
Islet size, µm2	2,444 ± 187	2,954 ± 311
Insulin-positive area, %‡	2.90 ± 0.66	2.73 ± 0.26
Glucagon-positive area, %	0.76 ± 0.08	0.87 ± 0.07
β-Cell mass, mg	83.50 ± 16.70	82.85 ± 8.49
α-Cell mass, mg	21.83 ± 2.47	26.67 ± 2.34
Islet vessel density, %	16.54 ± 0.69	17.23 ± 0.46
Pancreatic mRNA (ratio)
Insulin	1.00 ± 0.08	0.79 ± 0.04*
Glucagon‡	1.00 ± 0.21	0.84 ± 0.09
PDX1‡	1.00 ± 0.12	0.70 ± 0.04*
Glucokinase	1.00 ± 0.12	0.85 ± 0.10
GLUT2	1.00 ± 0.08	1.05 ± 0.09
IGF-1	1.00 ± 0.13	0.88 ± 0.18
IGF-2	1.00 ± 0.09	0.86 ± 0.11

Values are expressed as means ± SE; n = 7 for control and n = 10 for anemic.

^*P < 0.05, by Student's t-test or the Mann-Whitney U-test.

^‡Mann-Whitney U-test was performed.