Table 1.

Summary of fibrosis measures for treatment cohorts^*

	Control	Dox Week 3	Dox Week 7	Post-Dox Week 4
Hydroxyproline, mmol	1.22 [1.16, 1.31]	1.64 [1.50, 1.85]	3.90 [3.52, 4.35]	3.02 [2.57, 3.86]
Pleural thickness, μm	3.94 [3.51, 4.75]	13.6 [10.2, 19.4]	122.2 [96.4, 141.2]	16.5 [11.3, 21.3]
Histology score	0 [0, 0]	2.25 [2, 3]	4.80 [4, 5]	2.50 [2, 3]
Mean signal	0.186 [0.152, 0.217]	0.180 [0.174, 0.188]	0.266 [0.243, 0.403]	0.183 [0.166, 0.199]
High signal volume, %	16.0 [13.5, 19.6]	13.4 [12.1, 14.5]	32.7 [24.3, 43.1]	14.5 [11.68, 16.04]
Signal CV	1.21 [1.16, 1.33]	1.16 [1.13, 1.21]	1.06 [1.00, 1.21]	1.03 [0.98, 1.08]

CV, coefficient of variation.

^*Cohort means with the range of values within the cohort in brackets.