Figure 1.

The histologic sections of control group showed normal histoarchitecture, while pilocarpine-treated group (group II) exhibited condensation of pyramidal neurons with increased perineural space. In group III, normal morphology of DG was preserved by sodium valproate treatment. In group IV, histologic sections showed that treatment with pilocarpine and lower dose of naringenin resulted in mild condensation and degeneration of neurons in DG. Group V sections showed that treatment with pilocarpine and naringenin revealed almost normal neuronal morphology in the DG.