Fig. 8.

Acetylcholine (ACh)-mediated vasodilation in mesenteric arteries from rats exposed to sham and IH conditions. A: arteries were pretreated with vehicle (water) or the CSE inhibitor β-cyano-l-alanine (BCA; 100 µM) and then constricted to ~50% of their starting diameter with phenylephrine. Dilation to cumulative concentrations of ACh was measured. B: arteries were pretreated with vehicle (water) or the CSE inhibitor BCA (100 µM) and then constricted to ~50% of their starting diameter with phenylephrine. Dilation to 10 µM NaHS was measured. Values are means ± SE. *P < 0.05 vs. sham; n = 4–5 rats.