Site-specific immunoblotting for cMyBP-C phosphorylation. Left: representative images from Western blots using cMyBP-C phospho-specific antibodies against Ser-273 (A), Ser-282 (B), and Ser-302 (C) in whole heart homogenates from NTg-S, NTg-T, Tg-S, and Tg-T mice. STD is molecular weight standard. Right: quantification of cMyBP-C phosphorylation levels at: Ser-273 (A); Ser-282 (B), and Ser-302 (C). Data are represented as means ± SE; n = 6 hearts/group. Statistically significant result based on Tukey’s post hoc test: *P < 0.05. All samples were derived and processed at the same time and in parallel. Black lines demarcate spliced regions of interest.