ESRRβ localization and expression in human heart samples. A: immunostaining for ESRRβ (A), ESRRα (B), and N-Cadherin (C) in human transmural sections from arrhythmogenic right ventricular cardiomyopathy (ARVC) (n = 3), ischemic cardiomyopathy (iCM) (n = 3), hypertrophic cardiomyopathy (HCM) (n = 3), dilated cardiomyopathy (DCM) (n = 4), and control donor (n = 3) staining of human hearts. D: mRNA expression of ESRR isoforms and PGC-1 in nonfailing, ischemic cardiomyopathy (iCM) (n = 13) and dilated cardiomyopathy (DCM) (n = 13). *P < 0.05.