Fig. 11.
Effects of vacuum application and time on ventilation pressure traces in global edema model. A: representative airway pressure traces from cycles 3 and 100, without and with accelerated deflation, during ventilation between PAW of 6 and 18 cmH2O. Dashed lines indicate peak deflation rates and are reproduced at right to show change in deflation rate with time. B: after establishing global edema model baseline, 100 ventilation cycles, without or with accelerated deflation, increase peak deflation rate. *P < 0.05 vs. 3–7 cycles; #P < 0.05 vs. passive deflation.