Table 2.
Baseline markers summary and comparable values for HIV-negative population
| Marker | Baseline Median (Q1, Q3) | Non-HIV Median (Q1, Q3) |
|---|---|---|
| (CD4+) CD38+/DR+ [%] | 9.5 ( 7.6, 13.0) | 1.8 (1.5, 2.4)a; 2.0 (2.0, 3.0)b |
| (CD8+) CD38+/DR+ [%] | 14.9 ( 10.7, 19.5) | 4.1 (2.7, 6.0)a; 7.0 (5.0, 10.0)b |
| IL-6 [pg/mL] | 1.6 ( 1.1, 2.8) | 0.9 (0.6, 1.4)a; 1.0 (0.6, 1.2)b |
| D-dimer [ng/mL] | 178 ( 121, 272) | 192 (157, 240)a; 112 (83, 145)b |
| MCP-1 [pg/mL] | 229 ( 167, 276) | |
| IP-10 [pg/mL] | 146 ( 122, 210) | |
| CD40L [pg/mL] | 6450 ( 4402, 8912) | |
| sCD14 [ng/mL] | 1701 ( 1459, 2113) | 1271 (1100, 1464)a; 1326 (1186, 1599)b |
| P-Selectin [ng/mL] | 82 ( 55, 104) | |
| sCD163 [ng/mL] | 571 ( 462, 796) | 658 (610, 772)a |
| (CD14+/CD16−) CCR2+ [%] | 100 ( 99, 100) | |
| (CD14+/CD16−) CD40+ [%] | 32 ( 25, 42) | |
| (CD14+/CD16−) CX3CR1+ [%] | 4 ( 2, 7) | |
| (CD14+/CD16+) CCR2+ [%] | 94 ( 84, 97) | |
| (CD14+/CD16+) CD40+ [%] | 55 ( 39, 69) | |
| (CD14+/CD16+) CX3CR1+ [%] | 13 ( 8, 19) | |
| (CD14dim/CD16+) CCR2+ [%] | 9 ( 6, 13) | |
| (CD14dim/CD16+) CD40+ [%] | 76 ( 61, 84) | |
| (CD14dim/CD16+) CX3CR1+ [%] | 69 ( 51, 81) | |
| Fasting total cholesterol [mg/dL] | 182 ( 160, 202) | |
| Fasting triglycerides [mg/dL] | 114 ( 91, 155) | |
| Fasting HDL [mg/dL] | 48 ( 38, 63) | |
| Fasting LDL [mg/dL] | 104 ( 91, 117) | |
| Oxidized LDL [U/L] | 45 ( 38, 50) | |
| Lp-PLA2[ng/mL] | 146 ( 93, 179) | |
| CRP[ng/mL] | 2862 ( 1376, 9928) | 1127 (3467, 3176)a |