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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Metabolism. 2016 Dec 13;70:152–159. doi: 10.1016/j.metabol.2016.12.004

Figure 3.

Figure 3

MC4R null female mice have normal estrogenic responses on food intake and body weight. (A–B) Daily body weight of WT (A) and MC4R null (B) female mice after receiving ovariectomy plus estradiol-17β replacement (0.5 µg/day/mouse, OVX+E) or plus vehicle (OVX+V). N = 6/group. (C–D) Cumulative food intake of WT (C) and MC4R null (D) female mice after receiving OVX+E or OVX+V. N = 6/group. (E–F) Feed efficiency of WT (E) and MC4R null (F) female mice after receiving OVX+E or plus OVX+V. N = 6/group. Results are presented as mean ± SEM. *, P<0.05 in two way ANOVA analyses followed by post hoc Bonferroni tests.