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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Metabolism. 2016 Dec 13;70:152–159. doi: 10.1016/j.metabol.2016.12.004

Figure 4.

Figure 4

MC4R null female mice have normal estrogenic regulation on body fat, blood glucose and HPG axis. (A) Uterus weight measured 30 days after receiving OVX+E or OVX+V. N = 6/group. (B–D) Lean mass percentage (B), fat mass percentage (C) and gWAT weight (D) measured 30 days after receiving OVX+E or OVX+V. N = 6/group. (E–F) Fed glucose (E) and blood insulin (F) measured 30 days after receiving OVX+E or OVX+V. N = 6/group. (G–H) Relative mRNA levels of FSHβ (G) or LHβ (H) in the pituitary measured 30 days after receiving OVX+E or OVX+V. N = 6/group. Results are presented as mean ± SEM. *, P<0.05 in non-paired student’s t test.