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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Metabolism. 2017 Feb 2;70:12–22. doi: 10.1016/j.metabol.2017.01.030

Figure 1.

Figure 1

Glucose (A) and insulin (B) concentrations during oral glucose tolerance tests (OGTT) performed at baseline (●), and at one (■) and 12 (▲) months after bariatric/metabolic surgery. (A) Significant reductions in AUC glucose were observed at both one month (p=0.009) and 12 months (p<0.001) relative to baseline (pre-surgery). Glucose concentrations at the 120 min time point were similarly reduced at one month (*, p=0.020) and 12 months (**, p<0.001) relative to baseline (no statistical tests were conducted at other time points during the OGTT). (B) The rise in insulin secretion in the first 30 min relative to the rise in glucose concentrations (i.e., the insulinogenic index) was greater at one month (p=0.032) compared to baseline, but returned to baseline levels with a greater increase in insulin sensitivity by the 12-month time point.