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. 2017 Apr 7;2:25. [Version 1] doi: 10.12688/wellcomeopenres.11253.1

Figure 9. Determination of genes up-regulated with the onset of fetal testicular steroidogenesis.

Figure 9.

( a) Scatter plots showing changes in gene expression patterns for known testicular steroidogenic genes, LHCGR, STAR, CYP11A1, HSD3B2, CYP17A1 and HSD17B3. The plot shows normalised gene expression values for testis samples between approximately 46 and 74 dpc. Loess method was used for fitting a smooth curve between variables. ( b) Heatmap representing normalised gene expression values for the top 30 differentially up-regulated genes when comparing late (F1 to F3) ( N=8) and early (CS18 to CS22) ( N=9) testis samples. The intensity of gene expression is indicated by a colour scale: blue for lowest and red for highest expression levels. For all samples shown, P-value≤1e-4. Genes are ordered according to descending log 2FC values.